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Protocol for activity flow mapping of neurocognitive computations using the Activity Flow Toolbox

Date

March 2022

Location

Rutgers University, Newark, NJ

Role

First author

Project type

Peer-reviewed methods paper

Highlights

• Computational protocol that demonstrates how to use the Brain Activity Flow Toolbox
• Model the influence of task-evoked activity flowing over brain connections
• Empirically validate network mechanisms generating neurocognitive processes
• High prediction accuracy of activity flow mapped activations across cognitive domains

Cocuzza, C.V., Sanchez-Romero, R., & Cole, M.W. (2022). Protocol for activity flow mapping of neurocognitive computations using the Brain Activity Flow Toolbox. STAR Protocols, 3(1), 101094. https://doi.org/10.1016/j.xpro.2021.101094

Abstract
Traditional cognitive neuroscience uses task-evoked activations to map neurocognitive processes (and information) to brain regions, yet how those processes are generated is left unknown. We developed activity flow mapping to identify and empirically validate network mechanisms underlying the generation of neurocognitive processes. This approach models the movement of task-evoked activity over brain connections to predict task-evoked activations. We present a protocol for using the Brain Activity Flow Toolbox to identify network mechanisms underlying neurocognitive processes of interest.

pdf download: https://drive.google.com/file/d/1HDpUq0SWL-SnkJtKFpNbUeD1t3dxFR9Z/view?usp=sharing

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